Short answer: yes, but only if you get the placement and the quality right. An anti-fatigue mat works by encouraging tiny, constant muscle movements that keep blood flowing in the legs of someone standing in one spot — which is exactly what a nurse does at the station for hours.
The research on standing fatigue is consistent: people who stand on quality anti-fatigue matting report measurably less lower-body and back discomfort than those standing on hard floor. Our crews saw the same thing anecdotally on every floor we stocked.
The failure mode is treating it as decor. A thin mat tossed in a corner where nobody stands does nothing. The win is a quality mat placed exactly where staff plant themselves — the charting spot, the med station, the procedure room.
It’s genuinely the cheapest ergonomics upgrade on the floor, and it sits inside a bigger setup: mats where people stand, adjustable workstations where they chart, and lift gear where they move patients. The mat is the easy first win.
For the full breakdown, read our clinician ergonomics guide — it goes deeper than we can here.